Colne does not have a hotel, but there are lots of options nearby. Skipton has a Travel-lodge and is 20 mins away in the car. (Skipton is further north than Colne, if you are travelling from the south. En route, there are a lot of hotels, all the usuals, in Burnley, so this is definitely the best bet for convenience. Its then basically a couple of junctions up the motorway, as Burnely is also just of M65 too. Short journey - a pprox 15 mins drive to the lecture venue in Colne, or 20-30 mins on the bus from Burnley. Trains from Burnley go from Burnley CENTRAL, to Colne and take around 15 mins.
I haven't tested out the local accommodation, so check reviews on airbnb or tripadvisor etc.
There are some airbnb options in Colne. Other local places within 10-20 mins driving / uber from Colne that have airbnb options include Foulridge, Trawden, Barrowford, and various locations in Pendle. This is tourist country anyway - Pendle Witches, lots of walking tracks, plus near Skipton - gateway to Dales etc.